• QB Brock Purdy, San Francisco 49ers — over 250.5 yards (-115): The young passer currently claims the third-highest PFF passing grade (84.0) in the league and has surpassed that mark in three of his last four games.

• Record 2024: 11-13 (45.8%) – -2.14 units won.

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Estimated reading time: 4 minutes

Game overview

Week 6 begins with a highly anticipated matchup between NFC West division rivals. Seattle holds the top spot in the division and hosts the reigning NFC champion 49ers.

Although both franchises have strong squads, this does not mean that they have particularly solid results in the betting market, as both teams only managed three goals in total in ten meetings. San Francisco has been picking up points every week to start the season and has particularly struggled as away favorites, currently 0-2 against the team. On the other hand, the Seahawks are 0-2 in their last two games.

Both teams enter consecutive home losses as seven-point favorites, with Seattle falling to the Giants by nine points and San Francisco falling to a late field goal at Arizona.

The 49ers’ problems in the red zone have become a topic of conversation again this week after another poor performance. Against the Cardinals last week, the team managed six trips to the red zone but came away with just one touchdown. The 49ers have the fifth-lowest red zone touchdown percentage in the league (40.9%) despite having the highest average red zone snaps per game (14.2) in the NFL.

That could be a problem against the Seahawks’ defense, which seems to get stronger when secured inside its own 20-yard line. Although Seattle has allowed the second-most red zone drives (20), its red zone touchdown rate is just 45% – a top-10 mark among defenses. And most of that damage came in a single game, on the road against Detroit.

However, there were more favorable matchups in Seattle that support this number somewhat. Although the 49ers have struggled in some respects, they are undoubtedly one of the most talented offenses the Seahawks have faced this season.

WR DK Metcalf, Seattle Seahawks: Over 61.5 receiving yards (-110) – Variable PFF Greenline Edge

Despite some struggles last week, Metcalf is off to a fantastic start to the season. The sixth-year receiver has seen 42 targets – a top-10 mark at the position – allowing him to produce at a high level. Metcalf managed more than 100 receiving yards in three of his last four appearances, leading him to a top-25 ranking in yards per route run among receivers.

The job of guarding Metcalf will be the 49ers cornerback Charvarius Wardwho still has a lot of catching up to do after a difficult start to the year. Ward posted just a 43.2 PFF coverage grade over the last three games, ranking 92nd out of 99 qualified cornerbacks.

In previous matchups between these two, Ward has generally gotten the better of Metcalf, but this appears to be the Seahawks receiver’s chance to buck that trend. In addition to his on-field issues, Ward is also dealing with a knee injury that has limited him at practice this week. Considering that Ward won this duel thanks to his physical prowess, the hindrance of this injury could make it much more difficult to repeat this task.

QB Brock Purdy, San Francisco 49ers: Over 250.5 yards (-115) – 0.8% PFF Greenline Edge

Although the 49ers have questions to answer about their offensive efficiency, Purdy has played good ball through the first five games. The young passer currently claims the third-highest PFF passing grade (84.0) in the league and has surpassed that mark in three of his last four games.

Part of this is due to the 49ers playing good pass defense, especially in the last two games. In Weeks 4 and 5, San Francisco’s pass protection posted the team’s eighth-best pass-blocking rating (76.3), after surrendering zero sacks and posting a top-10 pass-blocking efficiency rating (85.4). had achieved.

That could prove to be a problem for Seattle, whose pass rushing production has declined recently. Through the first three games, the Seahawks applied the most pressure (70) in the NFL. But they have generated the fifth least in the last two weeks.

Without pressure, Purdy will be left to dismantle a secondary that may not have a cornerback Riq Woolen (Ankle), leaving cornerback Tre Brown (41.8 PFF coverage grade in the last three games) in a difficult situation.