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Predictions of how to see TNF
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Predictions of how to see TNF

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Week 6 of the 2024 NFL season begins with a massive NFC West matchup on “Thursday Night Football,” pitting the San Francisco 49ers (2-3) against the Seattle Seahawks (3-2).

Both teams are coming off a disappointing loss in Week 5 and will be looking to get back on the winning list in prime time at Lumen Field in Seattle. Both teams were up by 7 points at home and were upset on Sunday.

The Seahawks have lost two straight games after an impressive 3-0 start to the season under first-year head coach Mike Macdonald. Seattle was defeated by the New York Giants 29-20 on Sunday.

The reigning NFC champion 49ers suffered a 24:23 defeat at home against the Arizona Cardinals. It was a turbulent start to the season for San Francisco. Running back Christian McCaffrey remains out. Next up for the 49ers is a Super Bowl rematch with the Kansas City Chiefs in Week 7, but they can’t afford to ignore their division rivals on Thursday night.

Entering Week 6, both teams rank in the top ten in total offense (SF 2nd, 407.4 YDS/G) and (SEA 7th, 376.2 YDS/G). There is plenty of star power in both squads, which makes this match even more exciting.

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USA TODAY Sports will provide highlights, analysis and more from the Week 6 “Thursday Night Football” matchup between the Seahawks and 49ers.

  • Date: Thursday, October 10, 2024
  • Time: 8:15 p.m. ET

The Seahawks and 49ers game will open Week 6 of the 2024 NFL season on “Thursday Night Football” at 8:15 p.m. ET.

  • Live stream: Amazon Prime Video

“Thursday Night Football” streams exclusively on Amazon Prime Video.

Al Michaels (play-by-play) and Kirk Herbstreit (analyst) will be in the broadcast booth for Prime Video, while Kaylee Hartung (sideline) and Terry McAulay (rules analyst) will provide additional reporting.

Prime Video’s pregame, halftime and postgame shows feature Charissa Thompson as host and former NFL players Ryan Fitzpatrick, Tony Gonzalez, Richard Sherman and Andrew Whitworth as analysts. Taylor Rooks is the feature reporter for coverage of Prime Video’s “Thursday Night Football.”

Watch Thursday Night Football with a Prime Video subscription

Here are the USA TODAY Sports staff’s predictions for the Week 6 game on “Thursday Night Football”:

  • Lorenzo Reyes: 49ers 25, Seahawks 17
  • Tyler Dragon: 49ers 25, Seahawks 20
  • Jordan Mendoza: 49ers 26, Seahawks 20

According to BetMGM NFL odds, the 49ers are the favorites to win over the Seahawks in Week 6. Want to bet? Check out the best mobile sports betting apps offering NFL betting promotions in 2024, including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: 49ers (-3.5)
  • Money line: 49ers (-190); Sea Hawks (+155)
  • Over/under: 49

Not interested in this game? Check out our NFL betting odds, tips and spreads guide for Sunday Night Football odds and Monday Night Football odds.

New to sports betting? USA TODAY readers can score exclusive promos and bonus codes at the best online sportsbooks and sports betting sites.

Do you feel happy? Here you will find the best multiple bets and odds for this week’s NFL games

The Seahawks enter the Week 6 “TNF” showdown in sole possession of first place in the NFC West. However, with a win tonight, San Francisco could move into a tie.

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